8UBU
Cryo-EM structure of dimeric SCF-FBXL17-BACH1BTB E3 ligase complex close conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (A, H) | Cullin-1 | polymer | 764 | 88501.9 | 2 | UniProt (Q13616) Pfam (PF00888) Pfam (PF26557) Pfam (PF10557) | Homo sapiens (human) | CUL-1 |
| 2 | B, H (B, I) | E3 ubiquitin-protein ligase RBX1, N-terminally processed | polymer | 93 | 10840.4 | 2 | UniProt (P62877) Pfam (PF12678) | Homo sapiens (human) | E3 ubiquitin-protein transferase RBX1,N-terminally processed |
| 3 | C, F (C, G) | S-phase kinase-associated protein 1 | polymer | 162 | 18580.8 | 2 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) | Homo sapiens (human) | Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
| 4 | D, I (D, K) | F-box/LRR-repeat protein 17 | polymer | 392 | 44505.5 | 2 | UniProt (Q9UF56) Pfam (PF12937) Pfam (PF25372) Pfam (PF13516) | Homo sapiens (human) | |
| 5 | E, J (E, L) | Transcription regulator protein BACH1 | polymer | 122 | 13839.8 | 2 | UniProt (O14867) Pfam (PF00651) | Homo sapiens (human) |
Sequence modifications
C, G: 1 - 163 (UniProt: P63208)
| PDB | External Database | Details |
|---|---|---|
| - | Val 25 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 352536.9 | |
| All* | Total formula weight | 352536.9 |
