8U9L

Crystal Structure of RelA-cRel chimera complex with DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M (E, C, I, M)	DNA (5'-D(P*TP*TP*GP*AP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*GP*AP*TP*TP*C)-3')	polymer	20	6155.0	4		Homo sapiens
2	B, F, J, N (F, D, J, N)	DNA (5'-D(P*GP*AP*AP*TP*CP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*TP*CP*AP*A)-3')	polymer	20	6111.0	4		Homo sapiens
3	C, D, G, H, K... (A, B, G, H, K...)	Transcription factor p65,Proto-oncogene c-Rel chimera	polymer	277	31470.8	8	UniProt (Q04207) UniProt (P15307) Pfam (PF00554) Pfam (PF16179)	Mus musculus (house mouse)	Nuclear factor NF-kappa-B p65 subunit,Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Sequence modifications

A, B, G, H, K, L, O, P: 2 - 81 (UniProt: Q04207)

PDB	External Database	Details
Met 1	-	initiating methionine

A, B, G, H, K, L, O, P: 82 - 170 (UniProt: P15307)

PDB	External Database	Details
Glu 111	Gly 117	conflict
Pro 127	Gly 133	conflict
Leu 144	Cys 150	conflict
Cys 145	Val 151	conflict
Gln 147	Met 153	conflict
Val 148	Phe 154	conflict
His 154	Asp 160	conflict
Asp 171	-	linker
Asn 172	-	linker
Arg 173	-	linker
Ala 174	-	linker
Pro 175	-	linker
Asn 176	-	linker

A, B, G, H, K, L, O, P: 177 - 277 (UniProt: Q04207)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	300830.5
All*	Total formula weight	300830.5

*Water molecules are not included.