8U9L
Crystal Structure of RelA-cRel chimera complex with DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0003677 | molecular_function | DNA binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| H | 0003677 | molecular_function | DNA binding |
| H | 0003700 | molecular_function | DNA-binding transcription factor activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006355 | biological_process | regulation of DNA-templated transcription |
| K | 0003677 | molecular_function | DNA binding |
| K | 0003700 | molecular_function | DNA-binding transcription factor activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006355 | biological_process | regulation of DNA-templated transcription |
| L | 0003677 | molecular_function | DNA binding |
| L | 0003700 | molecular_function | DNA-binding transcription factor activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006355 | biological_process | regulation of DNA-templated transcription |
| O | 0003677 | molecular_function | DNA binding |
| O | 0003700 | molecular_function | DNA-binding transcription factor activity |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0006355 | biological_process | regulation of DNA-templated transcription |
| P | 0003677 | molecular_function | DNA binding |
| P | 0003700 | molecular_function | DNA-binding transcription factor activity |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PROSITE/UniProt
| site_id | PS01204 |
| Number of Residues | 7 |
| Details | REL_1 NF-kappa-B/Rel/dorsal domain signature. FRYkCEG |
| Chain | Residue | Details |
| A | PHE17-GLY23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine; by RPS6KA4 and RPS6KA5","evidences":[{"source":"UniProtKB","id":"Q04206","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 152 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"S-nitrosocysteine; alternate","evidences":[{"source":"PubMed","id":"22244329","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Modified residue: {"description":"N6-acetyllysine; by PCAF and EP300; alternate","evidences":[{"source":"UniProtKB","id":"Q04206","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q04206","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q04206","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q04206","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO3)","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 24 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO3); alternate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
