8U5I
Crystal Structure of human IDO1 bound to Compound 23
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Indoleamine 2,3-dioxygenase 1 | polymer | 394 | 44355.1 | 2 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | (1R,2S)-8-(ethanesulfonyl)-2-[(4R,5S,9aM)-5H-imidazo[5,1-a]isoindol-5-yl]-8-azaspiro[4.5]decan-1-ol | non-polymer | 401.5 | 2 | Chemie (W2Z) PubChem (129296705) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 478 | Chemie (HOH) |
Sequence modifications
A, B: 11 - 403 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Met 10 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 88710.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2036.0 | |
| All* | Total formula weight | 90746.2 |
