8U3A
TRPV1 in nanodisc bound with PI-Br4 bound in Conformation 1 (monomer)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, D) | Transient receptor potential cation channel subfamily V member 1 | polymer | 635 | 72888.2 | 2 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Norway rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | C (A) | (2S)-2-[(9,10-dibromooctadecanoyl)oxy]-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9R,10S)-9,10-dibromooctadecanoate | non-polymer | 1182.7 | 1 | Chemie (VPN) | |||
| 3 | D (A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 1 | Chemie (PCW) | |||
| 4 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | F, G (A, D) | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, D: 110 - 764 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Met 107 | - | initiating methionine |
| Gly 108 | - | expression tag |
| Ser 109 | - | expression tag |
| - | Asn 604 | deletion |
| - | Asn 605 | deletion |
| - | Ser 606 | deletion |
| - | Leu 607 | deletion |
| - | Pro 608 | deletion |
| - | Met 609 | deletion |
| - | Glu 610 | deletion |
| - | Ser 611 | deletion |
| - | Thr 612 | deletion |
| - | Pro 613 | deletion |
| - | His 614 | deletion |
| - | Lys 615 | deletion |
| - | Cys 616 | deletion |
| - | Arg 617 | deletion |
| - | Gly 618 | deletion |
| - | Ser 619 | deletion |
| - | Ala 620 | deletion |
| - | Cys 621 | deletion |
| - | Lys 622 | deletion |
| - | Pro 623 | deletion |
| - | Gly 624 | deletion |
| - | Asn 625 | deletion |
| - | Ser 626 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 145776.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1992.8 | |
| All* | Total formula weight | 147769.3 |
