8U2Z
TRPV1 in nanodisc bound with diC8-PIP2 in the dilated state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, B, C) | Transient receptor potential cation channel subfamily V member 1 | polymer | 635 | 72888.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Norway rat) | |
| 2 | E, J, K, Q (A, D, B, C) | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 4 | Chemie (PIO) | |||
| 3 | F, L, M, O (A, B, C) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 4 | Chemie (PCW) | |||
| 4 | G, I, N, P (A, D, B, C) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 5 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | R, S, T, U (A, D, B, C) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, D, B, C: 110 - 764 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Met 107 | - | initiating methionine |
| Gly 108 | - | expression tag |
| Ser 109 | - | expression tag |
| - | Asn 604 | deletion |
| - | Asn 605 | deletion |
| - | Ser 606 | deletion |
| - | Leu 607 | deletion |
| - | Pro 608 | deletion |
| - | Met 609 | deletion |
| - | Glu 610 | deletion |
| - | Ser 611 | deletion |
| - | Thr 612 | deletion |
| - | Pro 613 | deletion |
| - | His 614 | deletion |
| - | Lys 615 | deletion |
| - | Cys 616 | deletion |
| - | Arg 617 | deletion |
| - | Gly 618 | deletion |
| - | Ser 619 | deletion |
| - | Ala 620 | deletion |
| - | Cys 621 | deletion |
| - | Lys 622 | deletion |
| - | Pro 623 | deletion |
| - | Gly 624 | deletion |
| - | Asn 625 | deletion |
| - | Ser 626 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 291552.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 7704.4 | |
| All* | Total formula weight | 299257.3 |
