8TZB
Structure of the C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 2527 | 286462.8 | 1 | UniProt (Q5S007) Pfam (PF23744) Pfam (PF23745) Pfam (PF13855) Pfam (PF08477) Pfam (PF16095) Pfam (PF25497) Pfam (PF00069) Pfam (PF23748) | Homo sapiens (human) | |
| 2 | B (B) | designed ankyrin repeat proteins E11 | polymer | 182 | 19766.9 | 1 | synthetic construct | ||
| 3 | C (A) | 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide | non-polymer | 532.6 | 1 | Chemie (T3X) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 306229.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 532.6 | |
| All* | Total formula weight | 306762.3 |
