8TYP

Complement Protease C1s Inhibited by 6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Complement C1s subcomponent	polymer	344	38023.8	1	UniProt (P09871) Pfam (PF00084) Pfam (PF00089) In PDB	Homo sapiens (human)
2	B	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
3	A	6-(4-phenylpiperazin-1-yl)pyridine-3-carboximidamide	non-polymer		281.4	1	Chemie (SQT)
4		water	water		18.0	335	Chemie (HOH)

Sequence modifications

A: 358 - 688 (UniProt: P09871)

PDB	External Database	Details
Ala 356	-	expression tag
Glu 357	-	expression tag
Gly 689	-	expression tag
Ser 690	-	expression tag
Gly 691	-	expression tag
His 692	-	expression tag
His 693	-	expression tag
His 694	-	expression tag
His 695	-	expression tag
His 696	-	expression tag
His 697	-	expression tag
His 698	-	expression tag
His 699	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38023.8
Branched	Number of molecules	1
	Total formula weight	732.7
Non-Polymers*	Number of molecules	1
	Total formula weight	281.4
All*	Total formula weight	39037.8

*Water molecules are not included.