8TX4
Crystal Structure of rA3G-ssDNA-GA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA dC->dU-editing enzyme APOBEC-3G | polymer | 386 | 45199.6 | 1 | UniProt (M1GSK9) Pfam (PF18750) Pfam (PF18782) UniProt (by SIFTS) (Q7YR23) | Macaca mulatta (Rhesus monkey) | Deoxycytidine deaminase |
| 2 | B (B) | DNA 22-mer with (5'-D(P*TP*GP*AP*TP*TP)-3') | polymer | 22 | 6636.3 | 1 | synthetic construct | ||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A: 1 - 380 (UniProt: M1GSK9)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 139 | Cys 139 | conflict |
| Glu 140 | Gln 140 | conflict |
| Ala 141 | Lys 141 | conflict |
| - | Arg 142 | deletion |
| - | Asp 143 | deletion |
| - | Gly 144 | deletion |
| - | Pro 145 | deletion |
| Gly 142 | His 146 | conflict |
| Ala 259 | Glu 259 | conflict |
| Ile 381 | - | expression tag |
| Leu 382 | - | expression tag |
| Gln 383 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51835.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 225.8 | |
| All* | Total formula weight | 52061.7 |
