8TUC
Unphosphorylated CaMKK2 in complex with CC-8977
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 291 | 33127.3 | 1 | UniProt (Q96RR4) Pfam (PF00069) | Homo sapiens (human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 2 | B (A) | (4M)-2-cyclopentyl-4-(7-ethoxyquinazolin-4-yl)benzoic acid | non-polymer | 362.4 | 1 | Chemie (O7I) PubChem (166128272) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | I (A) | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A: 161 - 449 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Ser 159 | - | expression tag |
| Met 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33127.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 870.8 | |
| All* | Total formula weight | 33998.1 |
