8TTP
Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase | polymer | 361 | 39859.3 | 2 | UniProt (Q104Z6) Pfam (PF00144) UniProt (by SIFTS) (A0A377KDY3) | Escherichia coli A35218R | |
| 2 | C, O (A, B) | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | non-polymer | 267.3 | 2 | Chemie (NXL) | |||
| 3 | D, E, H, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 4 | F, Q (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | G, I (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 6 | S, T (A, B) | water | water | 18.0 | 887 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 388 (UniProt: Q104Z6)
| PDB | External Database | Details |
|---|---|---|
| Ser 28 | - | expression tag |
| Asn 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79718.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1487.6 | |
| All* | Total formula weight | 81206.2 |
