8TS7

Human PI3K p85alpha/p110alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	polymer	1063	123229.4	1	UniProt (P42336) Pfam (PF02192) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB	Homo sapiens (human)
2	B	Phosphatidylinositol 3-kinase regulatory subunit alpha	polymer	300	35960.1	1	UniProt (P27986) Pfam (PF00017) Pfam (PF16454) In PDB	Homo sapiens (human)

Sequence modifications

A: 2 - 1053 (UniProt: P42336)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Gly -6	-	expression tag
Ile -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag

B: 318 - 615 (UniProt: P27986)

PDB	External Database	Details
Gly 316	-	expression tag
Pro 317	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	159189.5
All*	Total formula weight	159189.5

*Water molecules are not included.