8TRV
Structure of the EphA2 LBDCRD bound to FabS1C_C1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, B) | Ephrin type-A receptor 2 | polymer | 308 | 33952.3 | 2 | UniProt (P29317) Pfam (PF01404) | Homo sapiens (human) | Epithelial cell kinase,Tyrosine-protein kinase receptor ECK |
| 2 | B, D (C, D) | S1C variant of Fab_C1 heavy chain | polymer | 223 | 23814.6 | 2 | Homo sapiens (human) | ||
| 3 | C, E (G, E) | S1C variant of Fab_C1 light chain | polymer | 215 | 23432.9 | 2 | Homo sapiens (human) | ||
| 4 | G, N, Q, S, W (A, G, D, E, B) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 5 | H, K, L, O, T... (A, C, G, E, B) | CHLORIDE ION | non-polymer | 35.5 | 10 | Chemie (CL) | |||
| 6 | I, J, M, R (A, C, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 7 | P (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) |
Sequence modifications
A, B: 23 - 326 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Leu 327 | - | expression tag |
| Val 328 | - | expression tag |
| Pro 329 | - | expression tag |
| Arg 330 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 162399.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1143.1 | |
| All* | Total formula weight | 163542.8 |
