8TRK
Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist methyl blue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, B) | P2X purinoceptor 7 | polymer | 595 | 68472.5 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) | Rattus | |
| 2 | D, FA, R (A, B, C) | 4,4',4''-[methanetriyltris(4,1-phenyleneazanediyl)]tri(benzene-1-sulfonic acid) | non-polymer | 757.9 | 3 | Chemie (KFM) | |||
| 3 | E, GA, S (A, B, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | F, G, HA, IA, T... (A, B, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | H, I, J, JA, K... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) | |||
| 6 | AA, BA, CA, DA, EA... (C, A, B) | PALMITIC ACID | non-polymer | 256.4 | 15 | Chemie (PLM) | Rattus | ||
| 7 | TA, UA, VA (A, C, B) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 205417.4 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 11160.1 | |
| All* | Total formula weight | 216577.5 |
