8TR7
Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist A839977
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 595 | 68472.5 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) | Rattus | |
| 2 | AA, D, P (C, A, B) | (1P)-1-(2,3-dichlorophenyl)-N-({2-[(pyridin-2-yl)oxy]phenyl}methyl)-1H-tetrazol-5-amine | non-polymer | 413.3 | 3 | Chemie (KDU) | |||
| 3 | BA, E, Q (C, A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | CA, DA, F, G, R... (C, A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | EA, FA, H, I, T... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | GA, HA, IA, J, JA... (C, A, B) | PALMITIC ACID | non-polymer | 256.4 | 15 | Chemie (PLM) | Rattus | ||
| 7 | O (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | Rattus | ||
| 8 | LA, MA, NA (A, B, C) | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 205417.4 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 8158.4 | |
| All* | Total formula weight | 213575.8 |
