8TR6
Cryo-EM structure of the rat P2X7 receptor in complex with the allosteric antagonist A438079
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor 7 | polymer | 595 | 68472.5 | 3 | UniProt (Q64663) Pfam (PF00864) Pfam (PF20478) | Rattus | |
| 2 | CA, D, Q (C, A, B) | 3-{[(5R)-5-(2,3-dichlorophenyl)tetrazolidin-1-yl]methyl}pyridine | non-polymer | 310.2 | 3 | Chemie (KE3) | |||
| 3 | DA, E, R (C, A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | EA, F, FA, G, S... (C, A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | GA, H, HA, I, IA... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) | |||
| 6 | AA, BA, JA, K, KA... (B, C, A) | PALMITIC ACID | non-polymer | 256.4 | 15 | Chemie (PLM) | Rattus | ||
| 7 | P (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | OA, PA, QA (A, B, C) | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 205417.4 | |
| Non-Polymers* | Number of molecules | 37 |
| Total formula weight | 8512.8 | |
| All* | Total formula weight | 213930.2 |
