8TR1
Crystal structure of trypanosome brucei hypoxanthine guanine phosphopribosyltransferase in complex with [2S,4R]-4-Guanin-9-yl-2-(2- phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 201 | 22420.8 | 4 | UniProt (Q07010) Pfam (PF00156) | Trypanosoma brucei | |
| 2 | E, F, G, H (A, B, C, D) | (3-{(2S,4R)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2-phosphonoethoxy)methyl]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid | non-polymer | 494.3 | 4 | Chemie (JEI) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 378 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 89683.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1977.3 | |
| All* | Total formula weight | 91660.4 |
