8TR1

Crystal structure of trypanosome brucei hypoxanthine guanine phosphopribosyltransferase in complex with [2S,4R]-4-Guanin-9-yl-2-(2- phosphonoethoxymethyl)-1-N-(3-phosphonopropionyl)pyrrolidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Hypoxanthine-guanine phosphoribosyltransferase	polymer	201	22420.8	4	UniProt (Q07010) Pfam (PF00156) In PDB	Trypanosoma brucei
2	A, B, C, D	(3-{(2S,4R)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2-phosphonoethoxy)methyl]pyrrolidin-1-yl}-3-oxopropyl)phosphonic acid	non-polymer		494.3	4	Chemie (JEI)
3		water	water		18.0	378	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	89683.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1977.3
All*	Total formula weight	91660.4

*Water molecules are not included.