8TQ5
Crystal structure of Fab DX17 in complex with MHC-I (HLA-B*44:05)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen B alpha chain (HLA-B*44:05) | polymer | 274 | 31802.1 | 1 | UniProt (Q860B7) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (P) | MHC class II antigen | polymer | 9 | 1090.2 | 1 | UniProt (Q9TQB0) | Homo sapiens (human) | |
| 4 | D (H) | Fab DX17 H-chain | polymer | 221 | 23629.6 | 1 | Mus musculus (mouse) | ||
| 5 | E (L) | Fab DX17 L-chain | polymer | 214 | 23843.4 | 1 | Mus musculus (mouse) | ||
| 6 | F (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G, H, I, J (A, B, H, L) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 2 - 274 (UniProt: Q860B7)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 92244.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 92465.8 |
