8TQ2
Structure of the kinase lobe of human CDK8 kinase module
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Mediator of RNA polymerase II transcription subunit 12 | polymer | 2177 | 243354.9 | 1 | UniProt (Q93074) Pfam (PF09497) Pfam (PF12145) Pfam (PF12144) | Homo sapiens (human) | |
| 2 | B (D) | Mediator of RNA polymerase II transcription subunit 13 | polymer | 2174 | 239535.9 | 1 | UniProt (Q9UHV7) Pfam (PF18296) Pfam (PF06333) | Homo sapiens (human) | Activator-recruited cofactor 250 kDa component,ARC250,Mediator complex subunit 13,Thyroid hormone receptor-associated protein 1,Thyroid hormone receptor-associated protein complex 240 kDa component,Trap240,Vitamin D3 receptor-interacting protein complex component DRIP250,DRIP250 |
| 3 | C (A) | Cyclin-dependent kinase 8 | polymer | 464 | 53368.7 | 1 | UniProt (P49336) Pfam (PF00069) | Homo sapiens (human) | |
| 4 | D (B) | Cyclin-C | polymer | 283 | 33279.7 | 1 | UniProt (P24863) Pfam (PF00134) Pfam (PF16899) | Homo sapiens (human) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 569539.2 | |
| All* | Total formula weight | 569539.2 |
