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8TPW

Crosslinked 6-deoxyerythronolide B synthase (DEBS) Module 3 in complex with antibody fragment 1B2: cis-oriented 1B2 and ACP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CEryAII,EryAII,EryAII,EryAII,6-deoxyerythronolide-B synthase EryA3, modules 5 and 6polymer1766186489.63UniProt (Q5UNP5)
In PDB
Saccharopolyspora erythraea
2HAntibody Fragment 1B2, Heavy Chainpolymer24926447.61Homo sapiens (human)
3LAntibody Fragment 1B2, Light Chainpolymer23625715.81Homo sapiens (human)
Sequence modifications
A, B, C: 3 - 1466 (UniProt: Q5UNP5)
PDBExternal DatabaseDetails
Met 0-expression tag
Ala 1-expression tag
Ser 2-expression tag
Thr 481Ser 480conflict
A, B, C: 1467 - 1765 (PDB: 8TPW)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight611632.2
All*Total formula weight611632.2
*Water molecules are not included.

223532

PDB entries from 2024-08-07

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