8TJC
Structure of human beta 1,3-N-acetylglucosaminyltransferase 2 with compound 8a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 | polymer | 397 | 46085.9 | 4 | UniProt (Q9NY97) Pfam (PF01762) | Homo sapiens (human) | Beta-1,3-N-acetylglucosaminyltransferase 1,BGnT-1,3-Gn-T1,Beta3Gn-T1,3-galactosyltransferase 7,3-GalTase 7,Beta3Gal-T7,Beta3GalT7,b3Gal-T7,Beta-3-Gx-T7,UDP-Gal:beta-GlcNAc beta-1,UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2,BGnT-2,3-Gn-T2,Beta3Gn-T2,UDP-galactose:beta-N-acetylglucosamine beta-1 |
| 2 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | G (G) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 5 | H (H) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G42227JK) | |||
| 6 | I (I) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 7 | J, M, Q, T (A, B, C, D) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 8 | K, N, R, U (A, B, C, D) | (6M)-1-[(2R)-3,3-dimethylbutan-2-yl]-6-[(5S)-5-methyl-4-oxo-5-phenyl-4,5-dihydro-1H-imidazol-2-yl]-1,3-dihydro-2H-benzimidazol-2-one | non-polymer | 390.5 | 4 | Chemie (HI8) | |||
| 9 | L, P (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 10 | O, S, V (B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 11 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 184343.6 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 3419.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2542.4 | |
| All* | Total formula weight | 190305.2 |
