8TJ4
CRYSTAL STRUCTURE OF THE A/Bangkok/1/1979(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLNLN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | Hemagglutinin HA1 chain | polymer | 323 | 35722.2 | 4 | UniProt (P03441) Pfam (PF00509) In PDB | Influenza A virus | |
| 2 | B, D, F, H | Hemagglutinin HA2 chain | polymer | 174 | 20055.2 | 4 | UniProt (P03441) Pfam (PF00509) In PDB | Influenza A virus | |
| 3 | I, L, O, S, T... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 9 | In PDB GlyTouCan (G42666HT) | |||
| 4 | J, M, N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | K, Q, R | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 3 | In PDB GlyTouCan (G22768VO) | |||
| 6 | P, Y | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 716.7 | 2 | In PDB GlyTouCan (G63564LA) | |||
| 7 | Z | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G09724ZC) | |||
| 8 | a, c | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 674.6 | 2 | In PDB GlyTouCan (G73578JC) | |||
| 9 | b, d | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | branched | 471.4 | 2 | In PDB GlyTouCan (G63069TR) | |||
| 10 | A, B, D, E, F... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 11 | B, F | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 12 | B, H | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 2 | Chemie (PG0) | |||
| 13 | E, F | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 14 | water | water | 18.0 | 1769 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 11 - 329 (UniProt: P03441)
B, D, F, H: 1 - 174 (UniProt: P03441)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Phe 294 | Unk 294 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 18 | Unk 347 | conflict |
| Asp 19 | Unk 348 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 223109.5 | |
| Branched | Number of molecules | 22 |
| Total formula weight | 13110.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2495.6 | |
| All* | Total formula weight | 238715.1 |
