8TIL

Human ACKR3 phosphorylated by GRK5 in complex with Arrestin3 reconstructed without receptor/micelle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	Fab7 heavy chain	polymer	240	25720.8	1		synthetic construct
2	B (L)	Fab7 light chain	polymer	215	23471.0	1		synthetic construct
3	C (R)	Atypical chemokine receptor 3	polymer	393	45356.4	1	UniProt (P25106) Pfam (PF00001)	Homo sapiens (human)	C-X-C chemokine receptor type 7,CXC-R7,CXCR-7,Chemokine orphan receptor 1,G-protein coupled receptor 159,G-protein coupled receptor RDC1 homolog,RDC-1
4	D (A)	Beta-arrestin-2	polymer	392	44106.3	1	UniProt (P32120) Pfam (PF00339) Pfam (PF02752)	Bos taurus (cattle)	Arrestin beta-2,Arrestin-3

Sequence modifications

R: 16 - 376 (UniProt: P25106)

PDB	External Database	Details
Gly 13	-	expression tag
Ala 14	-	expression tag
Pro 15	-	expression tag
Gly 377	-	expression tag
Arg 378	-	expression tag
Pro 379	-	expression tag
Leu 380	-	expression tag
Glu 381	-	expression tag
Val 382	-	expression tag
Leu 383	-	expression tag
Phe 384	-	expression tag
Gln 385	-	expression tag
Gly 386	-	expression tag
Pro 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag
His 393	-	expression tag
His 394	-	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
Asp 398	-	expression tag
Tyr 399	-	expression tag
Lys 400	-	expression tag
Asp 401	-	expression tag
Asp 402	-	expression tag
Asp 403	-	expression tag
Asp 404	-	expression tag
Lys 405	-	expression tag

A: 1 - 392 (UniProt: P32120)

PDB	External Database	Details
Val 362	Ala 362	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	138654.5
All*	Total formula weight	138654.5

*Water molecules are not included.