8TER

Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) P285L mutant, amyloid fiber

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	TRK-fused gene protein Low Complexity Domain P285L mutant	polymer	358	40464.8	20	UniProt (A0A2U3DNX3) UniProt (Q92734)	Purpureocillium lilacinum	TRK-fused gene protein, TFG
2	AA, BA, CA, DA, EA... (G, H, I, J, K...)	water	water		18.0	240	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T: -5 - 230 (UniProt: A0A2U3DNX3)

PDB	External Database	Details
Met -30	-	initiating methionine
Ser -29	-	expression tag
Tyr -28	-	expression tag
Tyr -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
Asp -20	-	expression tag
Tyr -19	-	expression tag
Asp -18	-	expression tag
Ile -17	-	expression tag
Pro -16	-	expression tag
Thr -15	-	expression tag
Thr -14	-	expression tag
Glu -13	-	expression tag
Asn -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Phe -9	-	expression tag
Gln -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Ala 231	-	linker
Gly 232	-	linker
Thr 233	-	linker
Met 234	-	linker
Asp 235	-	linker
Pro 236	-	linker

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T: 237 - 327 (UniProt: Q92734)

PDB	External Database	Details
Leu 285	Pro 285	variant

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	809295.1
All*	Total formula weight	809295.1

*Water molecules are not included.