8TDO
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, variant-type morphology
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, E | Transthyretin | polymer | 147 | 15878.9 | 4 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
Sequence modifications
A, B, C, E: -19 - 127 (UniProt: P02766)
PDB | External Database | Details |
---|---|---|
Ser 84 | Ile 104 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 63515.6 | |
All* | Total formula weight | 63515.6 |