8TCF
Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V heavy chain | polymer | 444 | 48310.5 | 1 | UniProt (P06756) Pfam (PF01839) | Homo sapiens (human) | |
| 2 | B (B) | Integrin beta-8 | polymer | 359 | 40268.0 | 1 | UniProt (P26012) Pfam (PF00362) | Homo sapiens (human) | |
| 3 | C (C) | Minibinder B8_BP_dslf | polymer | 75 | 8582.8 | 1 | synthetic construct | ||
| 4 | D (D) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G56014GC) | |||
| 5 | E, F, G (E, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 6 | H, I, J, K, M (A, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 7 | L, O, P, Q (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 8 | N (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 1 - 444 (UniProt: P06756)
B: 62 - 425 (UniProt: P26012)
| PDB | External Database | Details |
|---|---|---|
| Gly 400 | - | insertion |
| Cys 401 | Met 430 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 259 | Val 301 | conflict |
| - | Val 441 | deletion |
| - | Thr 442 | deletion |
| - | Gly 443 | deletion |
| - | Gly 444 | deletion |
| - | Lys 445 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 97161.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2346.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1109.5 | |
| All* | Total formula weight | 100617.0 |
