8TBB
F9S, novel TIM-3 targeting antibody, bound to IgV domain of TIM-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | T-cell immunoglobulin mucin receptor 3 | polymer | 110 | 12395.1 | 1 | UniProt (Q8TDQ0) Pfam (PF07686) | Homo sapiens (Human) | TIM-3,Hepatitis A virus cellular receptor 2, HAVcr-2,T-cell immunoglobulin and mucin domain-containing protein 3,TIMD-3,T-cell membrane protein 3 |
| 2 | B (H) | F9S Fab heavy chain | polymer | 226 | 24094.0 | 1 | Homo sapiens | ||
| 3 | C (L) | F9S Fab light chain | polymer | 214 | 23345.0 | 1 | Homo sapiens | ||
| 4 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (D, H, L) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 59834.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 60055.3 |
