8TB7
Cryo-EM Structure of GPR61-
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | G-protein coupled receptor 61,Soluble cytochrome b562 | polymer | 543 | 59991.9 | 1 | UniProt (Q9BZJ8) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361) In PDB | Homo sapiens (human) | |
2 | H | Fab24 BAK5 heavy chain | polymer | 490 | 52888.2 | 1 | Homo sapiens (human) | ||
3 | N | Fab hinge-binding nanobody | polymer | 122 | 13276.5 | 1 | Lama glama | ||
4 | L | Fab24 BAK5 light chain | polymer | 214 | 23398.1 | 1 | Homo sapiens (human) | ||
5 | R | 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-N-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-N-(2-methoxyethyl)pyridine-3-sulfonamide | non-polymer | 524.5 | 1 | Chemie (ZOB) | |||
6 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
R: 11 - 242 (UniProt: Q9BZJ8)
R: 248 - 352 (UniProt: P0ABE7)
R: 365 - 532 (UniProt: Q9BZJ8)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Tyr 2 | - | expression tag |
Pro 3 | - | expression tag |
Tyr 4 | - | expression tag |
Asp 5 | - | expression tag |
Val 6 | - | expression tag |
Pro 7 | - | expression tag |
Asp 8 | - | expression tag |
Tyr 9 | - | expression tag |
Ala 10 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Trp 254 | Met 29 | conflict |
Ile 349 | His 124 | conflict |
Leu 353 | - | linker |
Glu 354 | - | linker |
Arg 355 | - | linker |
Ala 356 | - | linker |
Arg 357 | - | linker |
Ser 358 | - | linker |
Thr 359 | - | linker |
Leu 360 | - | linker |
Gln 361 | - | linker |
Lys 362 | - | linker |
Glu 363 | - | linker |
Val 364 | - | linker |
PDB | External Database | Details |
---|---|---|
Ala 243 | - | linker |
Arg 244 | - | linker |
Arg 245 | - | linker |
Gln 246 | - | linker |
Leu 247 | - | linker |
Gly 533 | - | expression tag |
Ser 534 | - | expression tag |
Asp 535 | - | expression tag |
Tyr 536 | - | expression tag |
Lys 537 | - | expression tag |
Asp 538 | - | expression tag |
Asp 539 | - | expression tag |
Asp 540 | - | expression tag |
Asp 541 | - | expression tag |
Ala 542 | - | expression tag |
Lys 543 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 149554.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 524.5 | |
All* | Total formula weight | 150079.3 |