8TA3
Cryo-EM structure of the human CLC-2 chloride channel transmembrane domain Apo state with resolved N-terminal hairpin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Chloride channel protein 2 | polymer | 869 | 95487.6 | 2 | UniProt (P51788) Pfam (PF00654) | Homo sapiens (human) | ClC-2 |
| 2 | C, D (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) |
Sequence modifications
A, B: 1 - 869 (UniProt: P51788)
| PDB | External Database | Details |
|---|---|---|
| Ser 668 | Thr 668 | variant |
| - | Thr 806 | deletion |
| - | His 807 | deletion |
| - | Thr 808 | deletion |
| - | Ile 809 | deletion |
| - | Phe 810 | deletion |
| - | Ser 811 | deletion |
| - | Leu 812 | deletion |
| - | Leu 813 | deletion |
| - | Gly 814 | deletion |
| - | Val 815 | deletion |
| - | Asp 816 | deletion |
| - | His 817 | deletion |
| - | Ala 818 | deletion |
| - | Tyr 819 | deletion |
| - | Val 820 | deletion |
| - | Thr 821 | deletion |
| - | Ser 822 | deletion |
| - | Ile 823 | deletion |
| - | Gly 824 | deletion |
| - | Arg 825 | deletion |
| - | Leu 826 | deletion |
| - | Ile 827 | deletion |
| - | Gly 828 | deletion |
| - | Ile 829 | deletion |
| - | Val 830 | deletion |
| - | Thr 831 | deletion |
| - | Leu 832 | deletion |
| - | Lys 833 | deletion |
| - | Glu 834 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 190975.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 191046.2 |
