8T5W
Influenza PAN endonuclease I38T mutant with Baloxavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polymerase acidic protein | polymer | 192 | 22412.5 | 1 | UniProt (C3W5S0) | Influenza A virus (A/California/04/2009(H1N1)) | RNA-directed RNA polymerase subunit P2 |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, E (A) | Baloxavir acid | non-polymer | 483.5 | 2 | Chemie (E4Z) | |||
| 4 | F (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: 1 - 198 (UniProt: C3W5S0)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Thr 38 | Ile 38 | engineered mutation |
| Gly 64 | His 52 | conflict |
| - | Phe 53 | deletion |
| - | Ile 54 | deletion |
| - | Asp 55 | deletion |
| - | Glu 56 | deletion |
| - | Arg 57 | deletion |
| - | Gly 58 | deletion |
| - | Glu 59 | deletion |
| - | Ser 60 | deletion |
| - | Ile 61 | deletion |
| - | Ile 62 | deletion |
| - | Val 63 | deletion |
| - | Glu 64 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22412.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1076.9 | |
| All* | Total formula weight | 23489.3 |
