8T5L
Crystal structure of STING CTD in complex with 2'3'-cGAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Stimulator of interferon genes protein | polymer | 188 | 21557.2 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (B) | cGAMP | non-polymer | 674.4 | 1 | Chemie (1SY) | |||
| 3 | C (B) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
B: 154 - 341 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Ser 154 | Asn 154 | conflict |
| Ala 230 | Gly 230 | conflict |
| Arg 232 | His 232 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21557.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 674.4 | |
| All* | Total formula weight | 22231.6 |
