8T4Z
T-cell receptor and lipid complex structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antigen-presenting glycoprotein CD1d1 | polymer | 302 | 34662.0 | 1 | UniProt (P11609) Pfam (PF16497) Pfam (PF07654) | Mus musculus (house mouse) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11660.4 | 1 | UniProt (P01887) Pfam (PF07654) | Mus musculus (house mouse) | |
| 3 | C (C) | T cell receptor alpha variable 11, Human nkt tcr alpha chain chimera | polymer | 207 | 22779.2 | 1 | UniProt (A0A0B4J1J9) UniProt (K7N5M3) Pfam (PF07686) Pfam (PF09291) | Mus musculus (house mouse) | T cell receptor alpha variable 11D,Human nkt tcr beta chain |
| 4 | D (D) | Beta-chain, T cell receptor beta chain MC.7.G5 chimera | polymer | 242 | 27114.0 | 1 | UniProt (A2NTY6) UniProt (P0DTU4) Pfam (PF07686) Pfam (PF07654) | Mus musculus (house mouse) | TR beta chain TRBV25-1*01J2S3*01C2*01,MC.7.G5 TRB |
| 5 | E, G (E, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | H (A) | N-[(2R,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide | non-polymer | 648.1 | 1 | Chemie (Y73) | |||
| 8 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A: 1 - 279 (UniProt: P11609)
C: 1 - 93 (UniProt: A0A0B4J1J9)
C: 116 - 210 (UniProt: K7N5M3)
D: 0 - 95 (UniProt: A2NTY6)
D: 100 - 247 (UniProt: P0DTU4)
| PDB | External Database | Details |
|---|---|---|
| His 201 | Asp 219 | conflict |
| Gly 280 | - | expression tag |
| Ser 281 | - | expression tag |
| Leu 282 | - | expression tag |
| His 283 | - | expression tag |
| His 284 | - | expression tag |
| Ile 285 | - | expression tag |
| Leu 286 | - | expression tag |
| Asp 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Gln 289 | - | expression tag |
| Lys 290 | - | expression tag |
| Met 291 | - | expression tag |
| Val 292 | - | expression tag |
| Trp 293 | - | expression tag |
| Asn 294 | - | expression tag |
| His 295 | - | expression tag |
| Arg 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 18 | Cys 40 | conflict |
| Asp 94 | - | linker |
| Arg 95 | - | linker |
| Gly 96 | - | linker |
| Ser 97 | - | linker |
| Ala 98 | - | linker |
| Leu 99 | - | linker |
| Gly 100 | - | linker |
| Arg 103 | - | linker |
| Leu 104 | - | linker |
| His 105 | - | linker |
| Phe 106 | - | linker |
| Gly 107 | - | linker |
| Ala 108 | - | linker |
| Gly 109 | - | linker |
| Thr 110 | - | linker |
| Gln 111 | - | linker |
| Leu 112 | - | linker |
| Ile 113 | - | linker |
| Val 114 | - | linker |
| Ile 115 | - | linker |
D: 0 - 95 (UniProt: A2NTY6)
| PDB | External Database | Details |
|---|---|---|
| Asp 96 | - | linker |
| Glu 97 | - | linker |
| Gly 98 | - | linker |
| Tyr 99 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 115 | Thr 134 | conflict |
| Cys 174 | Ser 193 | conflict |
| Ala 192 | Cys 211 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96215.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 648.1 | |
| All* | Total formula weight | 98461.1 |
