8T4M
Closed human HCN1 F186C S264C bound to cAMP, reconstituted in LMNG + SPL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, C, B, A | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | polymer | 890 | 98871.8 | 4 | UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027) In PDB | Homo sapiens (human) | Brain cyclic nucleotide-gated channel 1,BCNG-1 |
2 | D, C, B, A | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 4 | Chemie (CMP) |
Sequence modifications
D, C, B, A: 1 - 890 (UniProt: O60741)
PDB | External Database | Details |
---|---|---|
Cys 186 | Phe 186 | engineered mutation |
Cys 264 | Ser 264 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 395487.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1316.8 | |
All* | Total formula weight | 396804.1 |