8T2H
DYRK1A complex with DYR530
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 365 | 42438.8 | 2 | UniProt (Q13627) Pfam (PF00069) | Homo sapiens (human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB |
2 | C, G (A, B) | (4P)-4-{(3M)-3-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]-2-methyl-3H-imidazo[4,5-b]pyridin-5-yl}pyridin-2-amine | non-polymer | 417.5 | 2 | Chemie (XIR) | |||
3 | D (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
4 | E, F, H (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | I, J (A, B) | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84877.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1305.5 | |
All* | Total formula weight | 86183.0 |