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8T2H

DYRK1A complex with DYR530

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dual specificity tyrosine-phosphorylation-regulated kinase 1Apolymer36542438.82UniProt (Q13627)
Pfam (PF00069)
Homo sapiens (human)Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB
2C, G
(A, B)
(4P)-4-{(3M)-3-[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]-2-methyl-3H-imidazo[4,5-b]pyridin-5-yl}pyridin-2-aminenon-polymer417.52Chemie (XIR)
3D
(A)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
4E, F, H
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
5I, J
(A, B)
waterwater18.0354Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight84877.6
Non-Polymers*Number of molecules6
Total formula weight1305.5
All*Total formula weight86183.0
*Water molecules are not included.

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PDB entries from 2024-12-25

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