8T1Q
Crystal structure of human CPSF73 catalytic segment in complex with compound 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cleavage and polyadenylation specificity factor subunit 3 | polymer | 479 | 54474.3 | 1 | UniProt (Q9UKF6) Pfam (PF00753) Pfam (PF10996) Pfam (PF07521) In PDB | Homo sapiens (human) | Cleavage and polyadenylation specificity factor 73 kDa subunit,CPSF 73 kDa subunit,mRNA 3'-end-processing endonuclease CPSF-73 |
2 | A | 3-[7,7-bis(oxidanyl)-8-oxa-7-boranuidabicyclo[4.3.0]nona-1,3,5-trien-5-yl]-~{N}-[3-(4-ethanoylphenyl)phenyl]propanamide | non-polymer | 416.3 | 1 | Chemie (XYX) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | A | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) | |||
6 | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 1 - 459 (UniProt: Q9UKF6)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54474.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 694.9 | |
All* | Total formula weight | 55169.2 |