8T1Q
Crystal structure of human CPSF73 catalytic segment in complex with compound 1
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS396 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17128255, ECO:0007744|PDB:2I7T, ECO:0007744|PDB:2I7V |
| Chain | Residue | Details |
| A | HIS71 | |
| A | HIS73 | |
| A | ASP75 | |
| A | HIS76 | |
| A | HIS158 | |
| A | ASP179 | |
| A | HIS418 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895 |
| Chain | Residue | Details |
| A | SER2 |
