8T1G
The crystal structure of hemagglutinin form a h7n9 influenza virus (a/shanghai/1/2013) in complex with antibody 1E11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Hemagglutinin HA1 | polymer | 321 | 34993.6 | 3 | UniProt (A0A8E4VRS4) UniProt (by SIFTS) (R4NN21) | Influenza A virus | |
| 2 | B, D, F (B, D, F) | Hemagglutinin HA2 | polymer | 210 | 24095.5 | 3 | UniProt (A0A8E4VRS4) UniProt (by SIFTS) (R4NN21) | Influenza A virus | |
| 3 | G, H, J (G, H, J) | 1E11 Fab Heavy chain | polymer | 232 | 24538.5 | 3 | Homo sapiens | ||
| 4 | I, K, L (I, K, L) | 1E11 Fab Light chain | polymer | 219 | 24162.0 | 3 | Homo sapiens | ||
| 5 | M, O, Q (M, O, Q) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 6 | N, R (N, R) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 7 | P (P) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 8 | S, V, Y (A, C, E) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 9 | AA, T, U, W, X... (F, A, B, C, D...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
B, D, F: 1 - 174 (UniProt: A0A8E4VRS4)
| PDB | External Database | Details |
|---|---|---|
| Leu 55 | Ile 394 | conflict |
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
| Gly 177 | - | expression tag |
| Tyr 178 | - | expression tag |
| Ile 179 | - | expression tag |
| Pro 180 | - | expression tag |
| Glu 181 | - | expression tag |
| Ala 182 | - | expression tag |
| Pro 183 | - | expression tag |
| Arg 184 | - | expression tag |
| Asp 185 | - | expression tag |
| Gly 186 | - | expression tag |
| Gln 187 | - | expression tag |
| Ala 188 | - | expression tag |
| Tyr 189 | - | expression tag |
| Val 190 | - | expression tag |
| Arg 191 | - | expression tag |
| Lys 192 | - | expression tag |
| Asp 193 | - | expression tag |
| Gly 194 | - | expression tag |
| Glu 195 | - | expression tag |
| Trp 196 | - | expression tag |
| Val 197 | - | expression tag |
| Leu 198 | - | expression tag |
| Leu 199 | - | expression tag |
| Ser 200 | - | expression tag |
| Thr 201 | - | expression tag |
| Phe 202 | - | expression tag |
| Leu 203 | - | expression tag |
| Ser 204 | - | expression tag |
| Gly 205 | - | expression tag |
| Arg 206 | - | expression tag |
| Leu 207 | - | expression tag |
| Val 208 | - | expression tag |
| Pro 209 | - | expression tag |
| Arg 210 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 323368.8 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4005.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1447.5 | |
| All* | Total formula weight | 328821.9 |
