8T1G
The crystal structure of hemagglutinin form a h7n9 influenza virus (a/shanghai/1/2013) in complex with antibody 1E11
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Hemagglutinin HA1 | polymer | 321 | 34993.6 | 3 | UniProt (A0A8E4VRS4) Pfam (PF00509) UniProt (by SIFTS) (R4NN21) In PDB | Influenza A virus | |
2 | B, D, F | Hemagglutinin HA2 | polymer | 210 | 24095.5 | 3 | UniProt (A0A8E4VRS4) Pfam (PF00509) UniProt (by SIFTS) (R4NN21) In PDB | Influenza A virus | |
3 | G, H, J | 1E11 Fab Heavy chain | polymer | 232 | 24538.5 | 3 | Homo sapiens | ||
4 | I, K, L | 1E11 Fab Light chain | polymer | 219 | 24162.0 | 3 | Homo sapiens | ||
5 | M, O, Q | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
6 | N, R | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
7 | P | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
8 | A, C, E | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
9 | F, A, B, C, D... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence modifications
B, D, F: 1 - 174 (UniProt: A0A8E4VRS4)
PDB | External Database | Details |
---|---|---|
Leu 55 | Ile 394 | conflict |
Gly 175 | - | expression tag |
Ser 176 | - | expression tag |
Gly 177 | - | expression tag |
Tyr 178 | - | expression tag |
Ile 179 | - | expression tag |
Pro 180 | - | expression tag |
Glu 181 | - | expression tag |
Ala 182 | - | expression tag |
Pro 183 | - | expression tag |
Arg 184 | - | expression tag |
Asp 185 | - | expression tag |
Gly 186 | - | expression tag |
Gln 187 | - | expression tag |
Ala 188 | - | expression tag |
Tyr 189 | - | expression tag |
Val 190 | - | expression tag |
Arg 191 | - | expression tag |
Lys 192 | - | expression tag |
Asp 193 | - | expression tag |
Gly 194 | - | expression tag |
Glu 195 | - | expression tag |
Trp 196 | - | expression tag |
Val 197 | - | expression tag |
Leu 198 | - | expression tag |
Leu 199 | - | expression tag |
Ser 200 | - | expression tag |
Thr 201 | - | expression tag |
Phe 202 | - | expression tag |
Leu 203 | - | expression tag |
Ser 204 | - | expression tag |
Gly 205 | - | expression tag |
Arg 206 | - | expression tag |
Leu 207 | - | expression tag |
Val 208 | - | expression tag |
Pro 209 | - | expression tag |
Arg 210 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 323368.8 | |
Branched | Number of molecules | 6 |
Total formula weight | 4005.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1447.5 | |
All* | Total formula weight | 328821.9 |