8SZE
Crystal structure of Yersinia pestis dihydrofolate reductase in complex with Trimethoprim
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Dihydrofolate reductase | polymer | 164 | 18336.6 | 2 | UniProt (A0A3N4BLI0) Pfam (PF00186) In PDB | Yersinia pestis | |
2 | A, B | TRIMETHOPRIM | non-polymer | 290.3 | 2 | Chemie (TOP) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
6 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 160 (UniProt: A0A3N4BLI0)
PDB | External Database | Details |
---|---|---|
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36673.3 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1457.0 | |
All* | Total formula weight | 38130.2 |