8SUF

The complex of TOL-1 ectodomain bound to LAT-1 Lectin domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	TIR domain-containing protein	polymer	1007	112253.8	4	UniProt (Q9N5Z3) Pfam (PF13855) Pfam (PF00560) In PDB	Caenorhabditis elegans
2	E, F, G, H	Latrophilin-like protein 1	polymer	114	12561.1	4	UniProt (G5EDW2) Pfam (PF02140) In PDB	Caenorhabditis elegans
3	I, M	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G22573RC)
4	J, K, N, O, R	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	5	In PDB GlyTouCan (G42666HT)
5	L	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
6	P	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
7	Q	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
8	D, A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)

Sequence modifications

A, B, C, D: 26 - 996 (UniProt: Q9N5Z3)

PDB	External Database	Details
Ala -6	-	expression tag
Asp -5	-	expression tag
Pro -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag
Gly 5	-	expression tag
Leu 6	-	expression tag
Asn 7	-	expression tag
Asp 8	-	expression tag
Ile 9	-	expression tag
Phe 10	-	expression tag
Glu 11	-	expression tag
Ala 12	-	expression tag
Gln 13	-	expression tag
Lys 14	-	expression tag
Ile 15	-	expression tag
Glu 16	-	expression tag
Trp 17	-	expression tag
His 18	-	expression tag
Glu 19	-	expression tag
Ala 20	-	expression tag
Asp 21	-	expression tag
Pro 22	-	expression tag
Gly 23	-	expression tag
Tyr 24	-	expression tag
Thr 25	-	expression tag
Asp 997	-	expression tag
Ile 998	-	expression tag
Gln 999	-	expression tag
His 1000	-	expression tag

E, F, G, H: 31 - 136 (UniProt: G5EDW2)

PDB	External Database	Details
Ala 29	-	expression tag
Asp 30	-	expression tag
His 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	499259.8
Branched	Number of molecules	10
	Total formula weight	5865.4
Non-Polymers*	Number of molecules	10
	Total formula weight	2212.1
All*	Total formula weight	507337.3

*Water molecules are not included.