8SRR
Cryo-EM structure of the CBC-ALYREF complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear cap-binding protein subunit 1 | polymer | 790 | 91960.3 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) | Homo sapiens (human) | 80 kDa nuclear cap-binding protein,CBP80,NCBP 80 kDa subunit |
| 2 | B (B) | Nuclear cap-binding protein subunit 2 | polymer | 156 | 18028.1 | 1 | UniProt (P52298) Pfam (PF00076) | Homo sapiens (human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
| 3 | C (C) | RNA and export factor binding protein 2 | polymer | 160 | 17542.9 | 1 | UniProt (Q4KL64) Pfam (PF00076) UniProt (by SIFTS) (Q9JJW6) | Mus musculus (house mouse) | |
| 4 | D (B) | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE | non-polymer | 458.2 | 1 | Chemie (M7G) |
Sequence modifications
C: 1 - 155 (UniProt: Q4KL64)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 127531.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 458.2 | |
| All* | Total formula weight | 127989.5 |
