8SR0
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | X, D | Lymphocyte activation gene 3 protein | polymer | 525 | 57508.3 | 2 | UniProt (P18627) In PDB | Homo sapiens (human) | LAG-3 |
2 | Y, H | favezelimab Fab heavy chain | polymer | 252 | 27245.7 | 2 | Mus musculus (mouse) | ||
3 | Z, L | favezelimab Fab light chain | polymer | 238 | 25915.6 | 2 | Mus musculus (mouse) | ||
4 | X, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 221339.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 221781.7 |