8SQK

SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase nsp12	polymer	929	106440.6	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB	Severe acute respiratory syndrome coronavirus 2	Pol,RdRp,Non-structural protein 12,nsp12
2	B, D	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp8
3	C	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTD1) Pfam (PF08716) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp7
4	G	Non-structural protein 9	polymer	113	12391.2	1	UniProt (P0DTD1) Pfam (PF08710) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp9
5	P	Primer RNA	polymer	32	10200.1	1		Severe acute respiratory syndrome coronavirus
6	T	Template RNA	polymer	35	11254.7	1		Severe acute respiratory syndrome coronavirus
7	O	SARS-CoV-2 5' UTR	polymer	20	6290.7	1		Severe acute respiratory syndrome coronavirus 2
8	A	5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine	non-polymer		459.3	2	Chemie (VSN)
9	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
10	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
11		water	water		18.0	131	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	199632.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1073.7
All*	Total formula weight	200705.8

*Water molecules are not included.