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8SQK

SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-directed RNA polymerase nsp12polymer929106440.61UniProt (P0DTD1)
Pfam (PF06478)
Pfam (PF00680)
Severe acute respiratory syndrome coronavirus 2Pol,RdRp,Non-structural protein 12,nsp12
2B, D
(B, D)
Non-structural protein 8polymer19821903.02UniProt (P0DTD1)
Pfam (PF08717)
Severe acute respiratory syndrome coronavirus 2nsp8
3C
(C)
Non-structural protein 7polymer839248.81UniProt (P0DTD1)
Pfam (PF08716)
Severe acute respiratory syndrome coronavirus 2nsp7
4E
(G)
Non-structural protein 9polymer11312391.21UniProt (P0DTD1)
Pfam (PF08710)
Severe acute respiratory syndrome coronavirus 2nsp9
5F
(P)
Primer RNApolymer3210200.11Severe acute respiratory syndrome coronavirus
6G
(T)
Template RNApolymer3511254.71Severe acute respiratory syndrome coronavirus
7H
(O)
SARS-CoV-2 5' UTRpolymer206290.71Severe acute respiratory syndrome coronavirus 2
8I, J
(A)
5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosinenon-polymer459.32Chemie (VSN)
9K, L
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
10M
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
11N, O, P, Q, R...
(A, B, C, P, T...)
waterwater18.0131Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight199632.2
Non-Polymers*Number of molecules5
Total formula weight1073.7
All*Total formula weight200705.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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