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8SP8

Human TRP channel TRPV6 in cNW30 nanodiscs inhibited by tetrahydrocannabivarin (THCV)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily V member 6polymer66676555.24UniProt (Q9H1D0)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF00520)
Homo sapiens (human)TrpV6,CaT-like,CaT-L,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
2E, F, G, GA, HA...
(A, C, B, D)
CHOLESTEROL HEMISUCCINATEnon-polymer486.712Chemie (Y01)
3AA, AB, CA, DA, EA...
(B, D, C, A)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.128Chemie (POV)
4BA, BB, FA, L, NA...
(B, D, C, A)
Tetrahydrocannabivarinnon-polymer286.48Chemie (I8E)
5Q
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6R
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight306220.8
Non-Polymers*Number of molecules50
Total formula weight29489.6
All*Total formula weight335710.5
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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