8SOB

Phosphoinositide phosphate 3 kinase gamma bound with ADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	phosphatidylinositol-4,5-bisphosphate 3-kinase	polymer	1108	127573.5	1	UniProt (A0A8D1WUA4) Pfam (PF19710) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O02697)	Sus scrofa (pig)
2	B (B)	Phosphoinositide 3-kinase regulatory subunit 5	polymer	890	98497.8	1	UniProt (A0A8D0T2D6) Pfam (PF10486) UniProt (by SIFTS) (O02696)	Sus scrofa (pig)
3	C (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Sequence modifications

A: 2 - 1102 (UniProt: A0A8D1WUA4)

PDB	External Database	Details
Met -5	-	initiating methionine
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

B: 1 - 877 (UniProt: A0A8D0T2D6)

PDB	External Database	Details
Gly 878	-	expression tag
Gly 879	-	expression tag
Gly 880	-	expression tag
Gly 881	-	expression tag
Ser 882	-	expression tag
Asp 883	-	expression tag
Tyr 884	-	expression tag
Lys 885	-	expression tag
Asp 886	-	expression tag
Asp 887	-	expression tag
Asp 888	-	expression tag
Asp 889	-	expression tag
Lys 890	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	226071.3
Non-Polymers*	Number of molecules	1
	Total formula weight	427.2
All*	Total formula weight	226498.5

*Water molecules are not included.