8SO3
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (D, X) | Lymphocyte activation gene 3 protein | polymer | 525 | 57508.3 | 2 | UniProt (P18627) | Homo sapiens (human) | LAG-3 |
| 2 | B, E (H, Y) | favezelimab Fab heavy chain | polymer | 252 | 27245.7 | 2 | Mus musculus (mouse) | ||
| 3 | C, F (L, Z) | favezelimab Fab light chain | polymer | 238 | 25915.6 | 2 | Mus musculus (mouse) | ||
| 4 | G, H, I, J (D, X) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 221339.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 222224.1 |
