8SIF
Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-101
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 159 | 18097.7 | 1 | UniProt (P26281) Pfam (PF01288) In PDB | Escherichia coli | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase,PPPK,7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase,HPPK |
| 2 | A | 5'-S-{(2R,4R)-1-[3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl]-2-carboxypiperidin-4-yl}-5'-thioadenosine | non-polymer | 600.6 | 1 | Chemie (ZX4) | |||
| 3 | water | water | 18.0 | 186 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18097.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 600.6 | |
| All* | Total formula weight | 18698.4 |
