8SHJ
Crystal structure of the WD-repeat domain of human WDR91 in complex with MR45279
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | WD repeat-containing protein 91 | polymer | 359 | 39515.8 | 3 | UniProt (A4D1P6) Pfam (PF00400) | Homo sapiens (human) | |
| 2 | D, E, F (A, B, C) | N-[3-(4-chlorophenyl)oxetan-3-yl]-4-[(3S)-3-hydroxypyrrolidin-1-yl]benzamide | non-polymer | 372.8 | 3 | Chemie (ZI8) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A, B, C: 392 - 732 (UniProt: A4D1P6)
| PDB | External Database | Details |
|---|---|---|
| Met 374 | - | initiating methionine |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| Ser 381 | - | expression tag |
| Ser 382 | - | expression tag |
| Gly 383 | - | expression tag |
| Arg 384 | - | expression tag |
| Glu 385 | - | expression tag |
| Asn 386 | - | expression tag |
| Leu 387 | - | expression tag |
| Tyr 388 | - | expression tag |
| Phe 389 | - | expression tag |
| Gln 390 | - | expression tag |
| Gly 391 | - | expression tag |
| - | Val 523 | deletion |
| - | Asp 524 | deletion |
| - | Phe 525 | deletion |
| - | Ser 526 | deletion |
| - | Ala 527 | deletion |
| - | Pro 528 | deletion |
| - | Asp 529 | deletion |
| - | Ile 530 | deletion |
| - | Gly 531 | deletion |
| - | Ser 532 | deletion |
| - | Lys 533 | deletion |
| - | Gly 534 | deletion |
| - | Met 535 | deletion |
| - | Asn 536 | deletion |
| - | Gln 537 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118547.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1118.5 | |
| All* | Total formula weight | 119665.9 |
