8SG5
Cytochrome P450 (CYP) 3A5 crystallized with clotrimazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Cytochrome P450 3A5 | polymer | 480 | 54862.6 | 8 | UniProt (P20815) Pfam (PF00067) | Homo sapiens (human) | CYPIIIA5,Cytochrome P450 HLp2,Cytochrome P450-PCN3 |
| 2 | CA, HA, I, MA, N... (E, F, A, G, B...) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 8 | Chemie (HEM) | |||
| 3 | AA, DA, EA, FA, IA... (D, E, F, A, G...) | 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE | non-polymer | 344.8 | 24 | Chemie (CL6) | |||
| 4 | BA, GA, LA, M, QA... (D, E, F, A, G...) | DODECYL NONA ETHYLENE GLYCOL ETHER | non-polymer | 582.8 | 7 | Chemie (CE9) |
Sequence modifications
A, B, C, D, E, F, G, H: 24 - 497 (UniProt: P20815)
| PDB | External Database | Details |
|---|---|---|
| Met 22 | - | initiating methionine |
| Ala 23 | - | expression tag |
| His 498 | - | expression tag |
| His 499 | - | expression tag |
| His 500 | - | expression tag |
| His 501 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 438900.7 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 17287.6 | |
| All* | Total formula weight | 456188.3 |
