8SF8
Structure of bovine PKA bound to (R)-N-(4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl)-2-amino-4-methylpentanamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41112.8 | 1 | UniProt (P00517) Pfam (PF00069) In PDB | Bos taurus (cattle) | PKA C-alpha |
2 | B | cAMP-dependent protein kinase inhibitor alpha | polymer | 20 | 2226.4 | 1 | UniProt (Q3SX13) In PDB | Bos taurus | PKI-alpha |
3 | A | N-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]-D-leucinamide | non-polymer | 322.4 | 1 | Chemie (ZWG) | |||
4 | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence modifications
A: 1 - 351 (UniProt: P00517)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43339.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 322.4 | |
All* | Total formula weight | 43661.6 |