8SDO
ATAD2 bromodomain in complex with "oncohistone" mutation H4S1CK5ac (res 1-15) ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATPase family AAA domain-containing protein 2 | polymer | 152 | 17858.2 | 1 | UniProt (Q6PL18) Pfam (PF00439) | Homo sapiens (human) | AAA nuclear coregulator cancer-associated protein,ANCCA |
| 2 | B (B) | Histone H4 | polymer | 15 | 1347.6 | 1 | UniProt (by SIFTS) (P62805) | Homo sapiens | |
| 3 | C, D (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A: 966 - 1112 (UniProt: Q6PL18)
| PDB | External Database | Details |
|---|---|---|
| Gly 961 | - | expression tag |
| Pro 962 | - | expression tag |
| Leu 963 | - | expression tag |
| Gly 964 | - | expression tag |
| Ser 965 | - | expression tag |
| Ala 1101 | Cys 1101 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19205.8 | |
| All* | Total formula weight | 19205.8 |
